Linked Life Data

3247877

Source:http://linkedlifedata.com/resource/pubmed/id/3247877

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-6-13
pubmed:abstractText
Following intraventricular injection of 5,7-dihydroxytryptamine in rats and survival periods up to 25 weeks, the supraependymal serotonergic axon plexus in the lateral and fourth ventricle, except for the plexus upon the hippocampal fimbria in some cases, showed no evidence of regenerative capacities. This contrasts with many reports on regeneration of intraparenchymal serotonergic fibre systems in the mammalian brain following mechanical or neurotoxin-induced experimental degeneration. The supraependymal plexus appears to be critically involved in maintainance of normal ependymal integrity in that following its experimentally induced death many ependymal cells exhibit various pathological alterations in all regions examined. Degeneration of this plexus is also associated with heavy phagocytotic reactions. Morphology, distribution and possible origins of supraependymal macrophages are briefly discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6225
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-31
pubmed:dateRevised
2006-7-19
pubmed:meshHeading
pubmed:articleTitle
Morphology of ventricular wall surfaces following neurotoxin induced degeneration of supraependymal afferents.
pubmed:affiliation
Department of Anatomy and Embryology, University of Groningen, Netherlands.
pubmed:publicationType
Journal Article