Linked Life Data

324487

Source:http://linkedlifedata.com/resource/pubmed/id/324487

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-6-30
pubmed:abstractText
The effect of 4-(2-hydroxy-3-isopropylamino-propoxy)-phenyl acetamide (atenolol, ICI 66 082) (100 mg) on airway resistance (Rt), thoracic gas volume (IGV), pulse rate and blood pressure was tested as a double blind study in 20 patients with chronic obstructive airway disease in comparison to propranolol (80 mg) and placebo. The effect on pulse rate was equipotent, but when using propranolol the mean increase of Rt was larger and increased Rt-values (greater than or equal 1.5 cm H2O/l/sec) were observed more frequently than after atenolol application. These differences were significant for 1 h after application. The augmentation of IGV was significantly larger after propranolol than after atenolol. We conclude that atenolol, in comparison to propranolol, has a relative but no specific cardioselectivity.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
419-22
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
[Effects of a new cardioselective beta-adrenergic blocker (atenolol) on airway resistance in chronic obstructive disease (author's transl)].
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Randomized Controlled Trial, Controlled Clinical Trial