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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
1989-5-16
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pubmed:abstractText |
Bile alcohol glucuronides present in human serum were isolated by ion exchange chromatography on piperidino-hydroxypropyl Sephadex LH-20. Following hydrolysis with beta-glucuronidase, the bile alcohols were analyzed by a combination of gas-liquid chromatography and mass spectrometry. Bile alcohols identified were 27-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25-pentol, 27-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25,26-hexol, 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25-pentol, 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,26-pentol, 5 beta-cholestane-3 alpha,7 alpha,12 alpha,25,26-pentol, and 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25,26-hexol. The bile alcohol composition in serum was similar to that in urine but not to that in bile. The concentration of total bile alcohols in serum was 59.5 +/- 24.6 micrograms/L.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0039-128X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
543-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3242175-Adult,
pubmed-meshheading:3242175-Bile,
pubmed-meshheading:3242175-Cholestanols,
pubmed-meshheading:3242175-Chromatography, Ion Exchange,
pubmed-meshheading:3242175-Female,
pubmed-meshheading:3242175-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:3242175-Humans,
pubmed-meshheading:3242175-Kidney,
pubmed-meshheading:3242175-Male
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pubmed:articleTitle |
Identification of bile alcohols in serum from healthy humans.
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pubmed:affiliation |
First Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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