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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1989-5-2
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pubmed:abstractText |
Epidemiological and genetic variables in clefts were analyzed during the years 1978-1986 in a case-control study of congenital malformations in the Emilia Romagna region of northern Italy. Among 150,168 newborns, 200 cases of cleft were detected, yielding a prevalence of 1.33 per 1,000. These clefts consisted of 112 (0.075%) cases of cleft lip with or without cleft palate (CL +/- P) and 88 cases (0.058%) of cleft palate (CP). Coexisting abnormalities were found in 32% of cases. The heritability coefficient of CL +/- P was 0.84. No cluster in time or space could be demonstrated. Epilepsy was the only maternal risk factor found to be correlated with clefts. A predominance of males was found among CL +/- P cases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0040-3709
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
559-64
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3238612-Cleft Lip,
pubmed-meshheading:3238612-Cleft Palate,
pubmed-meshheading:3238612-Consanguinity,
pubmed-meshheading:3238612-Cytogenetics,
pubmed-meshheading:3238612-Humans,
pubmed-meshheading:3238612-Infant, Newborn,
pubmed-meshheading:3238612-Italy,
pubmed-meshheading:3238612-Male,
pubmed-meshheading:3238612-Registries,
pubmed-meshheading:3238612-Risk Factors,
pubmed-meshheading:3238612-Sex Ratio
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pubmed:year |
1988
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pubmed:articleTitle |
Epidemiological and genetic study of 200 cases of oral cleft in the Emilia Romagna region of northern Italy.
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pubmed:affiliation |
Istituto di Genetica Medica, Università Ferrara, Italy.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|