Linked Life Data

323086

Source:http://linkedlifedata.com/resource/pubmed/id/323086

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-6-30
pubmed:abstractText
In a two-year study of 36 diabetic patients with retinopathy, proliferative in 18, first six months (period A) were spent in baseline. The patients then received calcium dobesylate, 250 mg three times a day (period B) and were then entered into the double blind part of the study, receiving either dobesylate for six months followed by placebo for a further six month period, or the reverse, according to a randomised code (period C and D). Cutaneous capillary resistance (CCR) which was abnormal in 26 patients at the beginning of the study had returned toward normal in 11 patients by the end of period B. However, this beneficial effect was not confirmed in the double blind part of the study. Punctate red spots (microaneurysms and microhemorrhages) were counted at the end of each period. No statistically significant differences were noted at any period studied. Retinal angiographic studies also failed to demonstrate any beneficial effect of the drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0338-1684
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
27-30
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
A controlled clinical trial of calcium dobesylate in the treatment of diabetic retinopathy.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial