Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-4-19
pubmed:abstractText
An endogenous brain lectin, with a great affinity for oligomannosidic glycans, called CSL (for 'cerebellar soluble lectin'), was detected on the surface of the cilia of ependymal cells both in cultures and in vivo. The lectin is not synthesized by the ependymal cells themselves. In vivo it is neither found in cerebrospinal fluid nor in cells of the choroid plexus. Probably, lectin CSL is produced by subependymal astrocytic cells. The membranes of ependymal cells seem to possess glycoprotein ligands for the lectin which explain the specific adhesion of CSL on the surface of these cells, particularly on the cilia. The localization of this adhesive molecule on cilia of ependymal cells suggests that it may play a role in trapping foreign cells, micro-organisms or debris.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0300-4864
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
745-51
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Endogenous lectin CSL is present on the membrane of cilia of rat brain ependymal cells.
pubmed:affiliation
Centre de Neurochimie du CNRS, Strasbourg.
pubmed:publicationType
Journal Article