Linked Life Data

3228982

Source:http://linkedlifedata.com/resource/pubmed/id/3228982

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-4-13
pubmed:abstractText
Serum cholesterol precursor levels and plant sterol were related to parameters of cholesterol metabolism in 22 patients with heterozygous familial hypercholesterolemia. The serum levels of cholesterol precursor sterols were inversely related to fractional absorption of dietary cholesterol and subsequently positively to overall cholesterol synthesis. The serum plant sterol levels, on the contrary, were significantly associated with fractional cholesterol absorption and negatively with overall cholesterol synthesis. These results were confirmed also with multivariate analyses. Fecal lanosterol, a cholesterol precursor, was related positively to cholesterol synthesis measured by sterol balance and serum precursors and negatively to serum plant sterols. The serum precursor and plant sterol levels were inversely significantly related to each other, indicating that the higher cholesterol absorption efficiency the higher are the serum plant sterol levels and the lower the precursor sterol contents and the overall cholesterol synthesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0009-8981
pubmed:author
pubmed:issnType
Print
pubmed:volume
178
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Serum noncholesterol sterols related to cholesterol metabolism in familial hypercholesterolemia.
pubmed:affiliation
Second Department of Medicine, University of Helsinki, Finland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't