Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1989-4-20
|
| pubmed:abstractText |
Partially purified kinin potentiating peptide (KPP) obtained from kininogen-depleted human plasma inhibited lung angiotensin converting enzyme in vitro and potentiated guinea-pig ileum contractions induced by bradykinin (BK), Lys-BK, Met-Lys-BK, Ile-Ser-BK, and Lys-Lys-BK. Contractions evoked by angiotensin II, histamine, acetylcholine, and barium chloride were not potentiated. KPP also potentiated kinin-induced contractions of rat uterus and of guinea-pig ileum pre-incubated with 1,10-phenanthroline. It is suggested that KPP potentiation is due, at least in part, to a direct effect on kinin receptor(s).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0100-879X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
21
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
453-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3228625-Animals,
pubmed-meshheading:3228625-Blood Proteins,
pubmed-meshheading:3228625-Bradykinin,
pubmed-meshheading:3228625-Drug Synergism,
pubmed-meshheading:3228625-Female,
pubmed-meshheading:3228625-Guinea Pigs,
pubmed-meshheading:3228625-Kinins,
pubmed-meshheading:3228625-Muscle Contraction,
pubmed-meshheading:3228625-Rats,
pubmed-meshheading:3228625-Uterine Contraction
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Characterization of a new kinin potentiating peptide obtained from human plasma proteins.
|
| pubmed:affiliation |
Departamento de Bioquímica, Universidade Federal do Rio de Janeiro, Brasil.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't
|