Linked Life Data

3228475

Source:http://linkedlifedata.com/resource/pubmed/id/3228475

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-4-14
pubmed:abstractText
In this paper we describe a new memory test in rats, based on the differential exploration of familiar and new objects. In a first trial (T1), rats are exposed to one or to two identical objects (samples) and in a second trial, to two dissimilar objects, a familiar (the sample) and a new one. For short intertrial intervals (approximately 1 min), most rats discriminate between the two objects in T2: they spend more time in exploring the new object than the familiar one. This test has several interesting characteristics: (1) it is similar to visual recognition tests widely used in subhuman primates, this allows interspecies comparisons; (2) it is entirely based on the spontaneous behavior of rats and can be considered as a 'pure' working-memory test completely free of reference memory component; (3) it does not involve primary reinforcement such as food or electric shocks, this makes it comparable to memory tests currently used in man.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0166-4328
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-59
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data.
pubmed:affiliation
Laboratoire de Psychophysiologie, Université Paris VII, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't