Linked Life Data

3227880

Source:http://linkedlifedata.com/resource/pubmed/id/3227880

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-3-27
pubmed:abstractText
Low values of mean capillary haematocrit have been reported in many tissues including skeletal muscle. The present study was undertaken to analyse haematocrit distribution in the transverse and terminal arterioles, capillaries and venules of the rabbit tenuissimus muscle preparation. Tube haematocrit, i.e. the volume fraction of red cells, in muscle capillaries (n = 85) was found to be 39% of systematic haematocrit Hsys. In part, this haematocrit reduction is due to the Fahraeus effect. Corresponding capillary discharge haematocrit HD was 56% of Hsys. Tenuissimus muscle capillaries are fed by terminal arterioles originating from transverse arterioles. The latter extend into and supply adjacent connective tissue septa in addition to the muscle tissue proper. In transverse arterioles leaving the muscle to enter the connective tissue, HD was found to be 127% of Hsys (n = 18), and in collecting venules at the muscle edge HD was 129% of Hsys (n = 18). These findings indicate that the connective tissue microcirculation represents a functional red-cell shunt in resting tenuissimus muscle. Since only about 20% of the inflow to the preparation passes through the connective tissue, this shunting is not sufficient to satisfy conservation of red-cell mass. In addition, it is likely that the observed low capillary haematocrit is in part due to a positive correlation between blood-flow velocity and HD in capillaries originating from individual terminal arterioles. This phenomenon is called the network Fahraeus effect.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0001-6772
pubmed:author
pubmed:issnType
Print
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
373-83
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Haematocrit distribution in rabbit tenuissimus muscle.
pubmed:affiliation
Pharmacia Experimental Medicine, La Jolla, CA 92037.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't