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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-3-31
pubmed:abstractText
An argon laser beam was used to irradiate the round window in 17 guinea pigs. Each animal was examined electrophysiologically with an electrode placed on the round window (RW) membrane 3 or 30 days after the irradiation, after which the cochlea was examined morphologically. The RW membrane was found intact in 16 out of 17 animals. All potentials (SP, CM, CAP) were abolished in 8 of the 17 animals. Histologically, perforations of the basilar membrane and Reissner's membrane were observed in 7 of 8 cases. In 4 of the 17 cases, a small effect of irradiation was evident both physiologically and histologically. Significant elevation of thresholds was observed in the remaining 5 animals, where amplitudes of CM, +SP, and CAP decreased at all intensities. Varying degrees of membranous labyrinth destruction can be used without perforating the RW membrane by the present method.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0365-5237
pubmed:author
pubmed:issnType
Print
pubmed:volume
456
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
92-7
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
An electrophysiological study on the effect of laser irradiation of round window membrane in the guinea pig.
pubmed:affiliation
Department of Otolaryngology, University of Tokyo, Japan.
pubmed:publicationType
Journal Article