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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1989-4-5
|
| pubmed:abstractText |
An anti-Purkinje cell antibody (APCA) was found in serum and CSF of 2 patients with paraneoplastic cerebellar degeneration (PDC) and breast carcinoma. Integrity of the blood-brain barrier (BBB) was normal in one patient and slightly damaged in the other. In both patients CSF IgG index was normal, but CSF/serum APCA ratio and CSF IgG APCA index were elevated suggesting that a selective concentration of the APCA in CSF occurs in patients with PCD. This feature supports the hypothesis that APCA may play a role in the pathogenesis of PCD.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0001-6314
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
78
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
210-3
|
| pubmed:dateRevised |
2006-8-16
|
| pubmed:meshHeading |
pubmed-meshheading:3227806-Adult,
pubmed-meshheading:3227806-Aged,
pubmed-meshheading:3227806-Autoantibodies,
pubmed-meshheading:3227806-Blood-Brain Barrier,
pubmed-meshheading:3227806-Breast Neoplasms,
pubmed-meshheading:3227806-Cerebellar Ataxia,
pubmed-meshheading:3227806-Cerebellar Diseases,
pubmed-meshheading:3227806-Female,
pubmed-meshheading:3227806-Humans,
pubmed-meshheading:3227806-Immunoglobulin G,
pubmed-meshheading:3227806-Paraneoplastic Syndromes,
pubmed-meshheading:3227806-Purkinje Cells
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Selective concentration of anti-Purkinje cell antibody in the CSF of two patients with paraneoplastic cerebellar degeneration.
|
| pubmed:affiliation |
Department of Neurology, Hospital Clinic i Provincial, Barcelona, Spain.
|
| pubmed:publicationType |
Journal Article
|