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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1989-4-5
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pubmed:abstractText |
Although neuroleptic malignant syndrome (NMS) was initially thought to be a rare, idiosyncratic complication, the incidence estimates have been rising over the years. A part of this increase can be explained on the basis of an over-inclusive definition of NMS. The unitary concept of NMS has been challenged recently and a spectrum concept has been enunciated on the basis of findings of retrospective chart-reviews which have used too broad a definition of NMS. The authors describe three cases of neuroleptic-related toxicity with different clinical presentations which appeared in a manner apparently supporting the spectrum concept. They discuss this controversial concept critically, however, and caution against its overzealous use in routine clinical practice owing to its far-reaching clinical implications.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0007-1250
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
153
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3224231-Adult,
pubmed-meshheading:3224231-Aged,
pubmed-meshheading:3224231-Blood Pressure,
pubmed-meshheading:3224231-Creatine Kinase,
pubmed-meshheading:3224231-Female,
pubmed-meshheading:3224231-Fever,
pubmed-meshheading:3224231-Humans,
pubmed-meshheading:3224231-Leukocyte Count,
pubmed-meshheading:3224231-Neuroleptic Malignant Syndrome,
pubmed-meshheading:3224231-Pulse
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pubmed:year |
1988
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pubmed:articleTitle |
Spectrum concept of neuroleptic malignant syndrome.
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pubmed:affiliation |
Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.
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pubmed:publicationType |
Journal Article,
Case Reports
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