Linked Life Data

3221873

Source:http://linkedlifedata.com/resource/pubmed/id/3221873

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1989-3-23
pubmed:abstractText
Among multiple subspecies of the protein kinase C (PKC) family, type I PKC from the hypothalamus, having the structure related to the gamma-sequence, responds to low concentrations of arachidonic acid to exhibit marked enzymatic activity. This mode of activation does not require elevated Ca2+ levels, nor does it depend on diacylglycerol and phospholipid. Type I PKC is expressed only in limited regions of central nervous tissues, such as the hypothalamus. This PKC subspecies is not detected in the pituitary gland. The results suggest that the activation of type I PKC may not always be directly associated with inositol phospholipid hydrolysis, and that this subspecies may play a role in the modulation of specialized functions of the hypothalamus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0888-8809
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1043-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Calcium-independent activation of hypothalamic type I protein kinase C by unsaturated fatty acids.
pubmed:affiliation
Department of Biochemistry, Kobe University School of Medicine, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't