Linked Life Data

3220246

Source:http://linkedlifedata.com/resource/pubmed/id/3220246

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-3-23
pubmed:abstractText
Twenty-six patients with chronic active liver disease (CALD) and a control group (8 patients with atrophic gastritis and 10 healthy people) underwent a microcytotoxicity (MCT) test using a primary line of human hepatocytes (5 1/2 month old human embryo) in the presence of rabbit complement. In 57.6% of the cases with CALD the test was positive (over 60% of hepatocytes lysed on contact with the patients' serum). The controls showed a negative MCT test, except for one case (12.5%) of atrophic gastritis. The positive results of the test in the CALD patients coincided with the evolutive stage of the disease and with obvious immune, humoral and cellularly, disturbances. The mechanism of the antibody dependent cytotoxicity mechanism in the hepatocytolysis in CALD is being demonstrated; the MCT test may be a marker of the evolution of the disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0435-1339
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
695-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Antibody dependent cytotoxicity in chronic active liver disease.
pubmed:affiliation
Fourth Medical Clinic, Public Health and Hygine Center, Timi?oara, Romania.
pubmed:publicationType
Journal Article, Comparative Study