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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1989-2-24
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pubmed:abstractText |
We evaluated the usefulness of both the Walter Reed (WR) staging classification and the component criteria used in the system in predicting progression to AIDS. The WR classification was applied to a cohort of 431 men who were seropositive for the human immunodeficiency virus on entry into a prospective study. The WR classification was of limited usefulness, as only 133 men (31%) could be assigned to a WR stage. Among men who could be WR classified, only individuals in WR stage 5 were found to have a significantly more rapid progression to AIDS. The seropositive cohort was also classified based on initial CD4 cell number. Low CD4 counts (less than 400 cells/mm3) were significantly associated with progression to AIDS, and grouping seropositive men by CD4 number alone provided as much prognostic information as the WR classification. Skin test anergy was also a significant predictor for progression to AIDS, but only in individuals with low CD4 counts.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:issn |
0894-9255
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
367-74
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3216317-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:3216317-Candidiasis, Oral,
pubmed-meshheading:3216317-Evaluation Studies as Topic,
pubmed-meshheading:3216317-HIV Seropositivity,
pubmed-meshheading:3216317-Humans,
pubmed-meshheading:3216317-Leukocyte Count,
pubmed-meshheading:3216317-Lymphatic Diseases,
pubmed-meshheading:3216317-Lymphocytes,
pubmed-meshheading:3216317-Prognosis,
pubmed-meshheading:3216317-Prospective Studies,
pubmed-meshheading:3216317-Severity of Illness Index,
pubmed-meshheading:3216317-Skin Tests,
pubmed-meshheading:3216317-Time Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Prognostic usefulness of the Walter Reed staging classification for HIV infection.
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pubmed:affiliation |
Department of Medicine, Northwestern University Medical School, Chicago, IL 60611.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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