Linked Life Data

3214552

Source:http://linkedlifedata.com/resource/pubmed/id/3214552

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1989-3-2
pubmed:abstractText
A highly sensitive, precise and fast automatic chromogen assay has been developed for estimation of elastase-type activity in plasma using 3-carboxypropionyl-trialanine p-nitro-anilide as substrate. The assay is linear up to at least 8.7 U/l and has a detection limit of 0.003 U/l. The study demonstrates that this enzyme activity is due to one or several metalloproteinases with pH optimum at physiological pH. The plasma enzyme activity in 37 healthy persons ranged from 0.10 U/l to 0.63 U/l. The individual day to day variation was found to be about 12%. In plasma pools prepared from randomly taken samples of in- and out-patients the activity was found up to 8.7 U/l. The origin of the metalloelastase activity is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0177-3593
pubmed:author
pubmed:issnType
Print
pubmed:volume
369
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
677-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A simple and sensitive chromogen assay for the measurement of elastase-type enzyme activity in human plasma.
pubmed:affiliation
National Institute of Occupational Health, Denmark.
pubmed:publicationType
Journal Article