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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1989-2-21
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pubmed:abstractText |
The metacarpophalangeal joint of the progressive ankylosis mouse was examined at 4, 6 and 8 weeks of age by using electron microscopy and electron probe microanalysis. These studies describe the progression of the disorder, and they reveal three overlapping phases: pannus proliferation, chondrophyte formation and mineralization, and articular cartilage mineralization. The chondrophyte mineralized in a manner fairly similar to endochondrial bone, whereas articular cartilage mineralized by advancement of a calcification front across the cartilage. Synovial crystal phagocytosis was also observed. The progressive ankylosis mouse should be an important model for studying both crystal deposition and abnormal articular cartilage calcification.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0002-9106
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
182
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-69
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3213824-Animals,
pubmed-meshheading:3213824-Ankylosis,
pubmed-meshheading:3213824-Female,
pubmed-meshheading:3213824-Finger Joint,
pubmed-meshheading:3213824-Male,
pubmed-meshheading:3213824-Metacarpophalangeal Joint,
pubmed-meshheading:3213824-Mice,
pubmed-meshheading:3213824-Mice, Mutant Strains,
pubmed-meshheading:3213824-Microscopy, Electron
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pubmed:year |
1988
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pubmed:articleTitle |
Ultrastructure of the mineralizing metacarpophalangeal joint of progressive ankylosis (ank/ank) mice.
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pubmed:affiliation |
Department of Human Anatomy, College of Medicine, Texas A&M University, College Station 77843.
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pubmed:publicationType |
Journal Article
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