Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1989-2-21
pubmed:abstractText
epsilon-Aminocapronic acid (1) as spacer was introduced in polymeric drugs on the basis of polyacrylic acid. Benzocain served as model drug. Polymeric drugs were synthesized by copolymerisation with free acrylic acid. Not all functional groups of the carrier reacted with the model drug. This product showed a strong swelling during the release of the covalently bound drugs. Pancreatin was used for this investigation. A raising of the splitting rate was achieved by incorporation of the spacer in the polymeric drugs. However, the low rate of cleaving is not relevant for practical use.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
692-3
pubmed:dateRevised
2007-1-29
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Preparation and testing of polymer drugs. 3. Binding of benzocaine to polyacrylic acid with a spacer].
pubmed:affiliation
Sektion Pharmazie, Martin Luther Universität Halle-Wittenberg, Saale.
pubmed:publicationType
Journal Article, English Abstract