Linked Life Data

3208227

Source:http://linkedlifedata.com/resource/pubmed/id/3208227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-2-17
pubmed:abstractText
Chickens homozygous for the epi gene (epileptics) suffer from spontaneous seizures throughout their life, whereas heterozygous (carriers) are phenotypically normal. Seizures can also be evoked in epileptics by photic stimulation. In addition, epileptic chickens' brains are 25% heavier than those of carriers. We have investigated whether hyperplasia or hypertrophy of astrocytes or increased numbers of astrocytic processes are involved in the development of seizures and the megalencephaly in this model by quantitative comparison of sections immunocytochemically stained for glial fibrillary acidic protein (GFAP). No statistically significant differences between epileptics and controls were found in any of seven areas selected for comparison. In this model gliosis is not involved in the development of epilepsy, nor does it result from repeated seizures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0317-1671
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
409-12
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Absence of gliosis in the brains of epileptic fowl.
pubmed:affiliation
Department of Pathology, University of Saskatchewan, Saskatoon, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't