Linked Life Data

3205880

Source:http://linkedlifedata.com/resource/pubmed/id/3205880

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-2-6
pubmed:abstractText
Body surface areas (BSA) were determined for strain 13 guinea pigs with body weights ranging from 191 to 1011 g. For this determination, the entire skin of each animal was removed immediately after death and flattened on a wax film with a homogeneous paper. The skin outlines on the paper were cut and weighed for determining BSA. The K value was calculated for each guinea pig as the ratio of BSA (cm2)/body weight (g)2/3. Significantly different K values of 11.31 +/- 0.11, 9.66 +/- 0.09, 9.22 +/- 0.05, and 9.17 +/- 0.05 were determined for average body weights of 218 +/- 24, 527 +/- 33, 706 +/- 60, and 943 +/- 30 g, respectively. By plotting these K values on semilog paper and determining the best fit curve of the slope, it was possible to extrapolate exponentially the K values for different body weights. The relationship between age and body weight was also established for guinea pigs, and a series of K values were determined from birth to 35 weeks of life. We conclude that a different K value should be used for calculating BSA for various ages and body weights of strain 13 guinea pigs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0037-9727
pubmed:author
pubmed:issnType
Print
pubmed:volume
189
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
285-90
pubmed:dateRevised
2007-11-2
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Body surface areas and K values in strain 13 guinea pigs with different body weights and ages.
pubmed:affiliation
Department of Clinical and Experimental Physiology, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21701-5011.
pubmed:publicationType
Journal Article