Linked Life Data

3204681

Source:http://linkedlifedata.com/resource/pubmed/id/3204681

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-2-1
pubmed:abstractText
Simultaneous cytogenetic and morphologic observations of single colonies derived from granulocytic precursor cells were performed on a patient with chronic myelogenous leukemia (CML) during the myeloid crisis. Colonies having a Ph1 chromosome and i(17q) were found to consist of neutrophilic/basophilic, eosinophilic/basophilic or basophilic granulocytes. These findings led to the conclusion that cells having the additional abnormality, i(17q), are still able to differentiate into neutrophil, basophil and eosinophil lineages. In other words, this chromosome abnormality does not give a proliferative advantage to a restricted cell lineage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0368-2811
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A clone with a chromosome abnormality, i(17q), in the myeloid crisis of chronic myeloid leukemia is able to differentiate into neutrophil, basophil and eosinophil lineages.
pubmed:affiliation
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't