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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-1-18
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pubmed:abstractText |
The hypothermia elicited in mice by intracerebroventricular injection (i.c.v.) of serotonin (5-HT) was studied. The 5-HT-induced hypothermia was attenuated by methysergide and pindolol, although ketanserin and p-chlorophenylalanine were without effect. These results suggest that 5-HT-induced hypothermia is produced by the direct activation of the 5-HT1 receptor. In addition, haloperidol, pimozide and alpha-MT inhibited 5-HT-induced hypothermia, which indicates that the dopaminergic systems are also involved in 5-HT-induced hypothermia in mice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0021-5198
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3199603-Animals,
pubmed-meshheading:3199603-Body Temperature Regulation,
pubmed-meshheading:3199603-Dopamine,
pubmed-meshheading:3199603-Hypothermia,
pubmed-meshheading:3199603-Injections, Intraventricular,
pubmed-meshheading:3199603-Male,
pubmed-meshheading:3199603-Mice,
pubmed-meshheading:3199603-Mice, Inbred ICR,
pubmed-meshheading:3199603-Receptors, Dopamine,
pubmed-meshheading:3199603-Receptors, Serotonin,
pubmed-meshheading:3199603-Serotonin
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pubmed:year |
1988
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pubmed:articleTitle |
The involvement of serotonergic and dopaminergic systems in hypothermia induced in mice by intracerebroventricular injection of serotonin.
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pubmed:affiliation |
Department of Pharmacology, Kobe Women's College of Pharmacy, Japan.
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pubmed:publicationType |
Journal Article
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