Linked Life Data

3199278

Source:http://linkedlifedata.com/resource/pubmed/id/3199278

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-1-26
pubmed:abstractText
Intestinal and pancreatic enzyme activities are known to respond to changes in dietary composition. Studies in rats and humans suggest that adaptive mechanisms differ between species in response to altered intakes of carbohydrate and fat. Because of increased use of the pig in the study of human nutrition, we compared the responses of pancreatic enzymes and intestinal disaccharidases in groups of 7- to 10-week-old pigs fed either high-carbohydrate/low-fat (70 cal% starch, 25% protein, 5% fat) or low-carbohydrate/high-fat (5, 25, 70%, respectively) diets for 7 and 30 days. No changes were observed in the activities for lactase, trypsin, or chymotrypsin or in the tissue protein concentrations, regardless of diet duration. High-carbohydrate/low-fat intake resulted in higher specific activities of sucrase, maltase, and amylase for both periods studied. Low-carbohydrate/high-fat intake resulted in higher specific activities of pancreatic lipase for both periods studied. The response of the intestinal disaccharidases differs from that observed previously in rodents but resembles the response reported in humans. Conversely, amylase and lipase responded similarly to the pattern in the rat. These data support the continued use of the pig as a suitable model in the study of adaptation to altered intakes of carbohydrate and fat.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0277-2116
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
914-21
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Effect of diet on intestinal and pancreatic enzyme activities in the pig.
pubmed:affiliation
Department of Pediatrics, University of Arizona College of Medicine, Tucson.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.