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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1989-1-17
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pubmed:abstractText |
Long-Evans rats with electrolytic hippocampal ablations exhibited chronic impairment in performance on a spatial delayed nonmatching-to-sample task in the arms of a T-maze. The same rats exhibited only mild deficits, which disappeared with practice in dispositional memory-dependent discrimination in the stem. Both types of discrimination were learned rapidly preoperatively with no marked positive or negative interaction between types of discrimination. The present results suggest that hippocampal lesions in rats have far more serious consequences on the performance of representational memory-dependent tasks than similar lesions in monkeys. In agreement with our past studies, the present experiment demonstrated that dispositional and representational memory systems in rodents have at least partially distinct anatomical substrates in brain.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0735-7044
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
102
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
635-42
|
pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3196433-Animals,
pubmed-meshheading:3196433-Discrimination Learning,
pubmed-meshheading:3196433-Exploratory Behavior,
pubmed-meshheading:3196433-Hippocampus,
pubmed-meshheading:3196433-Male,
pubmed-meshheading:3196433-Memory,
pubmed-meshheading:3196433-Rats,
pubmed-meshheading:3196433-Spatial Behavior
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pubmed:year |
1988
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pubmed:articleTitle |
Differential effects of hippocampal ablations on dispositional and representational memory in the rat.
|
pubmed:affiliation |
Center for Brain Research, University of Rochester Medical School, New York 14642.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|