Linked Life Data

3196073

Source:http://linkedlifedata.com/resource/pubmed/id/3196073

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-12-30
pubmed:abstractText
Flameless atomic absorption spectroscopy was used to measure lead concentrations in samples from 5 selected human skeletal sites (tibia, skull, rib, ilium, and vertebra) obtained from 134 hospital autopsies. Lead was distributed unequally among the different bones in distinct patterns that were age-, and to some extent, sex-dependent. To estimate lead concentration of the entire skeleton, all skeletal bones were divided into 5 groups based on their approximate compact/trabecular bone ratios, considering each of our 5 sampled sites to be the prototype for each such group. Regression analysis of the 10 possible bone site pair values at different ages yielded age-related constants. These constants were incorporated into an equation we developed that can be used both to estimate mean skeletal lead concentration (Pb) of the entire body skeleton and also to predict the lead concentration at any of the other 4 bone sites if any 1 of the 5 is measured. Applications of these data to in vivo bone lead measurements are detailed with respect to selection of the site to be measured, estimation of total skeletal lead burden, anticipated variations or error, and dependence of these factors on age and sex of the sampled population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-9896
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-91
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Lead in bone. IV. Distribution of lead in the human skeleton.
pubmed:affiliation
Department of Physiology, University of Minnesota-Duluth School of Medicine.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't