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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1988-12-30
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pubmed:abstractText |
Experiments were performed with bovine blood to study the response of the plasma/cell interface position to pumping rate adjustments in two single-stage (SS I and SS II) cell separation chambers. Standard clinical instrumentation and equipment and on-line computer interfacing were used to monitor and control the interface position. The data provided a quantitative description of its dynamics in the SS I and the SS II chambers. In the SS I chamber, adjustments in the flow rate caused the interface to move very slowly and in a complex manner from one steady-state operation position to another. Such behavior made both manual and computer-controlled operation very difficult. By contrast, the SS II chamber was inherently unstable for most operating conditions. We demonstrated, however, that a feedback controller could be used easily to adjust or maintain the interface position, and this system moved from one steady-state operating condition to another 10 times as fast as the system using the SS I chamber. Also, the manner in which the controller allowed the system to respond to operator requests was much simplier than that for the SS I system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0041-1132
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
588-92
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3194933-Animals,
pubmed-meshheading:3194933-Blood Component Removal,
pubmed-meshheading:3194933-Blood Flow Velocity,
pubmed-meshheading:3194933-Cattle,
pubmed-meshheading:3194933-Cell Separation,
pubmed-meshheading:3194933-Centrifugation,
pubmed-meshheading:3194933-Leukocyte Count,
pubmed-meshheading:3194933-Platelet Count
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pubmed:articleTitle |
Interface dynamics in a centrifugal cell separator.
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pubmed:affiliation |
Chemical Engineering Department, Washington State University, Pullman.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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