Linked Life Data

3194419

Source:http://linkedlifedata.com/resource/pubmed/id/3194419

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
1988-12-30
pubmed:abstractText
Several kinds of minisatellite DNA, all of which are composed of low to moderately repetitive DNA, have been identified in tetrapod genomes. While the repeating oligonucleotide elements (subrepeats) of a given minisatellite are virtually identical, subrepeat nucleotide composition differs between different minisatellites. Several minisatellites have exhibited moderate to high levels of restriction length polymorphism in a number of tetrapods. Such hypervariable markers provide powerful tools for genetic analyses in several fields of biology. Minisatellite applications have been restricted to tetrapods, but here we demonstrate that one probe, the M13 repeat probe previously used to detect minisatellites in humans and bovines, also reveals minisatellite-bearing endonuclease fragments in gymnosperms and angiosperms. While the plant minisatellites appear to be somatically stable within an individual, they often vary within species in potentially useful ways. These results demonstrate that minisatellite-like families may be distributed over a wide taxonomic range in eukaryotes, opening the possibility of a commensurately wide utility of minisatellite probes in genetic analyses.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-2423969, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-2880398, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-2892396, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-2989708, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-3029872, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-3287340, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-3347271, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-3574474, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-3574475, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-3856104, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-6096873, http://linkedlifedata.com/resource/pubmed/commentcorrection/3194419-6329026
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9176-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
M13 repeat probe detects DNA minisatellite-like sequences in gymnosperms and angiosperms.
pubmed:affiliation
Biology Department, Washington University, Saint Louis, MO 63130.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.