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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3-4
|
| pubmed:dateCreated |
1989-1-6
|
| pubmed:abstractText |
Vincristine sulfate (VCR) affects the fertilization ability of all germ-cell stages in male mice. The reduced fertilization ability leads to a pseudo-dominant-lethal effect and sterile matings. The frequency of these effects is dose-dependent. The frequency of specific-locus mutations was not increased by VCR in male mice following 2 mg/kg bw treatment.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0027-5107
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
209
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
107-13
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3193974-Animals,
pubmed-meshheading:3193974-Dose-Response Relationship, Drug,
pubmed-meshheading:3193974-Fertilization,
pubmed-meshheading:3193974-Male,
pubmed-meshheading:3193974-Mice,
pubmed-meshheading:3193974-Mutagenicity Tests,
pubmed-meshheading:3193974-Spermatozoa,
pubmed-meshheading:3193974-Vincristine
|
| pubmed:articleTitle |
Mutagenicity testing of vincristine sulfate in germ cells of male mice.
|
| pubmed:affiliation |
Institut für Säugetiergenetik, Gesellschaft für Strahlen- und Umweltforschung (GSF), Neuherberg, F.R.G.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|