Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1988-12-27
pubmed:abstractText
A new x-ray-based (dual-energy x-ray absorptiometry [DEXA]) instrument for measurement of bone mineral in the spine and hips (QDR-1000, Hologic, Inc.) was compared with a commercial dual photon absorptiometry (DPA) instrument that uses a 153Gd source (DP3, Lunar Radiation Corporation). Measurements were made on phantoms and lumbar spines of patients to study accuracy, precision, limitations, and compatibility of results between instruments. Both instruments measure bone mineral of integral bone in terms of area bone density with an entrance exposure of less than 5 mR. For spinal bone mineral measurements, the DEXA instrument had a shorter scanning time and higher resolution images than the DPA system. The DEXA instrument also showed better precision in a spine phantom and reduced influence of thickness for patient measurement. For bone mineral content, accuracy was about equal for both instruments; for measurements of the area of the region of interest, accuracy was better with the DEXA instrument. With both instruments, fat had little effect on bone mineral density in bone phantom studies. Measurements on both instruments were influenced by the location of a bone phantom within the photon beam. Results in patients showed good correlation (r = 0.988) for bone mineral density. Measurements of bone mineral density in patients were consistently lower with the DEXA instrument because of better accuracy in area measurements. The new x-ray-based instrument is a major advance in bone mineral absorptiometry and provides improved, yet less expensive, measurements in research and clinical applications.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0025-6196
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1075-84
pubmed:dateRevised
2007-10-29
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Comparison of dual-energy x-ray absorptiometry and dual photon absorptiometry for bone mineral measurements of the lumbar spine.
pubmed:affiliation
Section of Diagnostic Nuclear Medicine, Mayo Clinic, Rochester, MN 55905.
pubmed:publicationType
Journal Article, Comparative Study