Linked Life Data

3192899

Source:http://linkedlifedata.com/resource/pubmed/id/3192899

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-1-9
pubmed:abstractText
Cardiac baroreflex sensitivity (BRS; i.e. the slope of the line relating change in pulse interval to change in systemic arterial pressure) was assessed in response to an increase in mean blood pressure (MBP) evoked by methoxamine or a decrease evoked by sodium nitroprusside. Measurements were made in Long Evans (i.e. control) and in Brattleboro (i.e. vasopressin (AVP)-deficient) rats, following acute and chronic intravascular catheterization, and in water-replete and water-deprived states (the latter designed to reduce plasma volume and activate AVP-dependent mechanisms (in Long Evans rats]. There were no differences between the corresponding values for cardiac BRS in Long Evans and Brattleboro rats. Furthermore, water deprivation caused no significant changes in cardiac BRS in either strain. These results do not support the claim that absence of endogenous AVP in Brattleboro rats is associated with marked impairment of cardiac BRS, and indicate that chronic changes in circulating AVP do not cause systematic changes in cardiac BRS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0165-1838
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Cardiac baroreflex sensitivities in conscious, unrestrained, Long Evans and Brattleboro rats.
pubmed:affiliation
Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Nottingham, U.K.
pubmed:publicationType
Journal Article, Comparative Study