|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1989-1-12
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|
pubmed:abstractText |
Calcium D-pantothenate (Ca D-P) and calcium D-homopantothenate (Ca D-HP) (pantogam) exhibiting antagonism in a number tests of pharmacological screening were shown to inhibit the absorption of [14C]-GABA (0.2 microM) by the rat brain cortex slices (3 mm) incubated in calcium-free medium. The effect of Ca D-HP manifests at its low concentrations (10(-6) M) and that of Ca D-P at high concentrations (10(-6) M). The data obtained are discussed in relation to the possible influence of the anion and cation components of the studied compounds.
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|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0014-8318
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
51
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
25-9
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:3191967-Absorption,
pubmed-meshheading:3191967-Animals,
pubmed-meshheading:3191967-Carbon Radioisotopes,
pubmed-meshheading:3191967-Cerebral Cortex,
pubmed-meshheading:3191967-Culture Techniques,
pubmed-meshheading:3191967-Dose-Response Relationship, Drug,
pubmed-meshheading:3191967-GABA Antagonists,
pubmed-meshheading:3191967-Male,
pubmed-meshheading:3191967-Pantothenic Acid,
pubmed-meshheading:3191967-Rats,
pubmed-meshheading:3191967-Rats, Inbred Strains,
pubmed-meshheading:3191967-Structure-Activity Relationship,
pubmed-meshheading:3191967-gamma-Aminobutyric Acid
|
|
pubmed:articleTitle |
[The effect of calcium pantothenate and homopantothenate on [14C]-GABA absorption by slices of rat cerebral cortex].
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|
