Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1988-12-27
|
pubmed:abstractText |
Discrete bilateral lesions were placed into the sexually dimorphic nucleus (SDN) of the medial preoptic area (MPOA) of ovariectomized female Wistar rats, chronically treated with testosterone (T). Effects of these lesions upon masculine and feminine sexual behavior were studied by comparing the results of pre- and postoperative tests, using sham-operated and unoperated females as controls. Bilaterally-lesioned and, to a lesser extent, unilaterally-lesioned females, showed a marked and significant reduction of masculine sexual behavior (i.e., mounting), especially in the first postoperative tests. Feminine sexual responses, i.e., receptive and proceptive behavior, although slightly lower in bilaterally-lesioned females, did not change significantly. Sexual partner preference, operationalized as the choice between a receptive female and a sexually active male, remained unaffected by the lesions. Plasma levels of testosterone were similar in the various groups. It is concluded that the SDN may be functionally implicated in the control of masculine sexual behavior in T-treated females.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0361-9230
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
215-24
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3191408-Animals,
pubmed-meshheading:3191408-Brain Diseases,
pubmed-meshheading:3191408-Female,
pubmed-meshheading:3191408-Preoptic Area,
pubmed-meshheading:3191408-Rats,
pubmed-meshheading:3191408-Rats, Inbred Strains,
pubmed-meshheading:3191408-Sexual Behavior, Animal,
pubmed-meshheading:3191408-Testosterone
|
pubmed:year |
1988
|
pubmed:articleTitle |
Effects of lesions of the sexually dimorphic nucleus on sexual behavior of testosterone-treated female Wistar rats.
|
pubmed:affiliation |
Netherlands Institute for Brain Research, Amsterdam.
|
pubmed:publicationType |
Journal Article
|