Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-12-27
pubmed:abstractText
Discrete bilateral lesions were placed into the sexually dimorphic nucleus (SDN) of the medial preoptic area (MPOA) of ovariectomized female Wistar rats, chronically treated with testosterone (T). Effects of these lesions upon masculine and feminine sexual behavior were studied by comparing the results of pre- and postoperative tests, using sham-operated and unoperated females as controls. Bilaterally-lesioned and, to a lesser extent, unilaterally-lesioned females, showed a marked and significant reduction of masculine sexual behavior (i.e., mounting), especially in the first postoperative tests. Feminine sexual responses, i.e., receptive and proceptive behavior, although slightly lower in bilaterally-lesioned females, did not change significantly. Sexual partner preference, operationalized as the choice between a receptive female and a sexually active male, remained unaffected by the lesions. Plasma levels of testosterone were similar in the various groups. It is concluded that the SDN may be functionally implicated in the control of masculine sexual behavior in T-treated females.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0361-9230
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
215-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Effects of lesions of the sexually dimorphic nucleus on sexual behavior of testosterone-treated female Wistar rats.
pubmed:affiliation
Netherlands Institute for Brain Research, Amsterdam.
pubmed:publicationType
Journal Article