Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1989-1-12
|
| pubmed:abstractText |
Childhood non-Hodgkin's lymphomas (NHL) are a heterogeneous group. Biological studies have shown that most mediastinal NHL are lymphoblastic lymphomas which are T-cell tumors. In contrast, most NHL occurring in the gastrointestinal tract, abdominal cavity and Waldeyer's ring are diffuse undifferentiated small non-cleaved lymphomas, mainly Burkitt's or Burkitt-like lymphomas. Different multi-drug combinations have been proposed over the last 20 years. The LSA2-L2 regimen or other protocols, based on acute lymphoblastic leukemia results, have improved the prognosis in T-cell NHL. In extended B-cell NHL, aggressive short term multi-drug chemotherapy given in pulses gives a cure rate above 60%. The use of surgery and radiotherapy in the treatment of childhood NHL has decreased with the realisation that most children can be cured by chemotherapy alone.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0753-3322
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
42
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
263-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading | |
| pubmed:year |
1988
|
| pubmed:articleTitle |
Childhood non-Hodgkin's lymphomas: clinical and therapeutic aspects.
|
| pubmed:affiliation |
Pédiatrie, Hôpital Charles Nicolle, Rouen, France.
|
| pubmed:publicationType |
Journal Article
|