Linked Life Data

3190545

Source:http://linkedlifedata.com/resource/pubmed/id/3190545

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1988-11-29
pubmed:abstractText
Ciliary muscle topography and connective tissue distribution were studied by light microscopy in atropinized, pilocarpinized, or untreated eyes from rhesus monkeys of various ages. With age, the connective tissue ground plate between ciliary muscle and ciliary processes thickens, while there is very little increase in connective tissue within the ciliary muscle. With age, the atropinized muscle becomes shorter and smaller in area while it remains unchanged in width and position. In pilocarpinized eyes, the ciliary muscle is shorter, narrower, smaller in longitudinal and total area (ie, more circular and compact), and positioned more anteriorly than in contralateral atropinized eyes. These contractile responses to pilocarpine diminish with age at a rate similar to that for accommodative decline. According to these topographic findings, physicians seeking the pathophysiologic characteristics of presbyopia, which occurs in humans and rhesus monkeys on a comparable relative time scale, should redirect their attention toward the ciliary muscle.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0003-9950
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1591-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Age-related loss of morphologic responses to pilocarpine in rhesus monkey ciliary muscle.
pubmed:affiliation
Department of Anatomy, University of Erlangen-Nürnberg, West Germany.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't