Linked Life Data

3189878

Source:http://linkedlifedata.com/resource/pubmed/id/3189878

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-12-15
pubmed:abstractText
We have studied the effects of air drying of exposed, acid etched dentin on the sensory innervation of rat molars. In the acute series of experiments, trigeminal nerve fibers were labeled by axonal transport of radioactive protein prior to the dentin exposure and desiccation, the anesthetized rats were fixed by aldehyde perfusion 10 min later, and the teeth were prepared for autoradiography. The results confirmed the hydrodynamic theory by showing outward movement of labeled nerve material in response to dentinal drilling and desiccation. It also showed that some odontoblasts could be separated from the dentinal nerve fibers. In the chronic series, teeth were injured 25 h, 5-7 days, or 21 days prior to fixation and nerves were labeled during the last 24 hours; the surviving vital nerve fibers were evident because of their axonal transport of the radioactive label. In that series, sensory nerve fibers were found to have been lost from areas with newly-formed reparative dentin, or from dentinal tubules that had lost their odontoblasts. In the teeth injured 25 h, 5-7 days, or 21 days earlier, an abnormal nonneuronal labeling occurred 0.2-0.3 mm into injured dentin. Our results are discussed in relation to the hydrodynamic theory, nerve-odontoblast interactions, differences between shallow and deep cavity injuries, altered nerve location in response to pulpal or dentinal injury, and characteristics of the pulp-dentin border.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-276X
pubmed:author
pubmed:issnType
Print
pubmed:volume
221
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
872-83
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Acute and chronic reactions of dental sensory nerve fibers to cavities and desiccation in rat molars.
pubmed:affiliation
Department of Anesthesiology, University of Washington, Seattle 98195.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't