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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1988-12-20
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pubmed:abstractText |
Several investigators have documented a rearrangement of the breakpoint cluster region (bcr) in selected patients with a morphologic diagnosis of chronic myelogenous leukemia (CML) but no abnormality of the Philadelphia chromosome (Ph) by cytogenetic studies. Our intention was to systematically investigate the incidence of the bcr rearrangement in such patients, and to correlate the findings with patient characteristics, response to therapy (especially alpha interferon treatment), and overall prognosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0002-9343
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
639-44
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3189367-Adolescent,
pubmed-meshheading:3189367-Adult,
pubmed-meshheading:3189367-Aged,
pubmed-meshheading:3189367-Female,
pubmed-meshheading:3189367-Gene Rearrangement,
pubmed-meshheading:3189367-Humans,
pubmed-meshheading:3189367-Immunoblotting,
pubmed-meshheading:3189367-Interferon Type I,
pubmed-meshheading:3189367-Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative,
pubmed-meshheading:3189367-Leukemia, Myelomonocytic, Chronic,
pubmed-meshheading:3189367-Male,
pubmed-meshheading:3189367-Middle Aged,
pubmed-meshheading:3189367-Molecular Probes,
pubmed-meshheading:3189367-Philadelphia Chromosome,
pubmed-meshheading:3189367-Prognosis,
pubmed-meshheading:3189367-Recombinant Proteins
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pubmed:year |
1988
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pubmed:articleTitle |
Significance and correlations of molecular analysis results in patients with Philadelphia chromosome-negative chronic myelogenous leukemia and chronic myelomonocytic leukemia.
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pubmed:affiliation |
Department of Hematology, M.D. Anderson Hospital and Tumor Institute, Houston 77030.
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pubmed:publicationType |
Journal Article
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