Linked Life Data

3186986

Source:http://linkedlifedata.com/resource/pubmed/id/3186986

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-12-15
pubmed:abstractText
The relaxation effects and organ distribution of superparamagnetic iron oxide particles for magnetic resonance imaging were measured in rats. T1 and T2 were measured for excised organs, and tissue iron levels were quantified with radiolabeling. Approximately 70% of the injected dose is present in the liver and 10% in the spleen 1 hour after injection. At 20 MHz, the doses required to reduce liver and spleen T2 to half the normal value, as measured with a Carr-Purcell-Meiboom-Gill sequence, were, respectively, 420 and 830 mumol iron injected per kilogram of rat. The transverse relaxation rates increase linearly with injected dose and showed no evidence of saturation. These results suggest that this material is less effective than previously suggested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0033-8419
pubmed:author
pubmed:issnType
Print
pubmed:volume
169
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
653-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Quantitation of MR relaxation effects of iron oxide particles in liver and spleen.
pubmed:affiliation
Department of Diagnostic Radiology, Yale School of Medicine, New Haven, CT 06510.
pubmed:publicationType
Journal Article