Linked Life Data

3185974

Source:http://linkedlifedata.com/resource/pubmed/id/3185974

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-11-30
pubmed:abstractText
Isolated rat neurohypophyses were superfused in vitro and the release of vasopressin and oxytocin determined by radioimmunoassays. Hormone release was evoked by short trains of electrical stimulation (10 s), at frequencies from 15 to 100 Hz. The release of oxytocin evoked by stimulation up to 80 Hz was increased 2- to 3-fold in the presence of naloxone. The evoked release of vasopressin was not significantly affected by naloxone. In conclusion, opioid inhibition of oxytocin release operates also under stimulation conditions which mimic the electrical activity (i.e. short bursts of high frequencies) of physiologically activated (e.g. by suckling) oxytocinergic neurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
114-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Endogenous opioid inhibition of the release of oxytocin from the isolated rat neurohypophysis during high-frequency stimulation of the pituitary stalk.
pubmed:affiliation
Department of Pharmacology, University of Mainz, F.R.G.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't