Linked Life Data

3185116

Source:http://linkedlifedata.com/resource/pubmed/id/3185116

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1988-12-7
pubmed:abstractText
The phospholipid composition and fatty acid profiles of human eosinophils were studied. Extremely high levels of ether phospholipids were found in this type of cell, such as alkylacylglycerophosphocholine (GPC) and alkenylacylglycerophosphoethanolamine (GPE); these two ether phospholipids accounted for about three-fourths of the choline and ethanolamine glycerophospholipids (CGP and EGP), respectively. Fatty acid analyses revealed that very large portions of arachidonic acid (20:4) were esterified to alkylacyl-GPC (92.0% in CGP) and alkenylacyl-GPE (86.6% in EGP), respectively. While high amounts of alkylacyl-GPC and the abundance of 20:4 in this ether phospholipid have been observed in other types of blood cells of various animals, these percentages for human eosinophils are the highest among such cells. These results suggest that alkyl and alkenyl ether phospholipids play essential roles in human eosinophils in various physiological and pathological conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0024-4201
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
815-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Phospholipid analysis of human eosinophils: high levels of alkylacylglycerophosphocholine (PAF precursor).
pubmed:affiliation
Faculty of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan.
pubmed:publicationType
Journal Article