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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1988-11-30
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pubmed:abstractText |
We characterized the effect of infection with human immunodeficiency virus type 1 (HIV) on levels of total immunoglobulins and pneumococcal vaccine-specific immunoglobulins in 28 heterosexual and 25 homosexual men seronegative for HIV; 27 asymptomatic, seropositive homosexual men; and 21 patients with AIDS. Total serum IgG levels were increased in both HIV-seropositive groups compared with the HIV-seronegative men (P less than .001). Total IgM levels, however, were elevated only in the asymptomatic, HIV-seropositive men (P less than .08); total IgA levels were elevated only in the patients with AIDS (P less than .05). Vaccine-specific serum IgG, IgM, and IgA significantly increased over baseline three and six weeks after immunization in all groups (P less than .05). Responses to vaccine among the HIV-seronegative groups were similar but were greater for all antibody classes than were responses among the HIV-seropositive groups (P less than .05).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-1899
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
983-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3183430-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:3183430-Adult,
pubmed-meshheading:3183430-Antibodies, Bacterial,
pubmed-meshheading:3183430-Bacterial Vaccines,
pubmed-meshheading:3183430-HIV Seropositivity,
pubmed-meshheading:3183430-HIV-1,
pubmed-meshheading:3183430-Homosexuality,
pubmed-meshheading:3183430-Humans,
pubmed-meshheading:3183430-Immunoglobulin A,
pubmed-meshheading:3183430-Immunoglobulin G,
pubmed-meshheading:3183430-Immunoglobulin M,
pubmed-meshheading:3183430-Immunoglobulins,
pubmed-meshheading:3183430-Male,
pubmed-meshheading:3183430-Middle Aged,
pubmed-meshheading:3183430-Pneumococcal Vaccines,
pubmed-meshheading:3183430-Streptococcus pneumoniae
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pubmed:year |
1988
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pubmed:articleTitle |
Class-specific antibody response to pneumococcal capsular polysaccharides in men infected with human immunodeficiency virus type 1.
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pubmed:affiliation |
Infectious Disease Section, Veterans Administration Medical Center, Minneapolis, Minnesota 55417.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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