Linked Life Data

3180504

Source:http://linkedlifedata.com/resource/pubmed/id/3180504

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-12-12
pubmed:abstractText
Pallister syndrome is consequent to mosaicism for i(12p). The isochromosome is found mainly in skin fibroblast cultures, but rarely also in cultured peripheral blood lymphocytes. Maternal age for reported cases of Pallister syndrome was significantly older (p less than 0.005) compared to maternal age for the general population, and similar to maternal age in cases of Down syndrome (p less than 0.5). Paternal age in cases of Pallister syndrome was that expected in the general population from the age of their spouses (p less than 0.9). These data complement the maternal age effect seen in other aneuploidy conditions and suggest, as is found in mosaic cases of Down syndrome, that the chromosomally normal cell line in Pallister syndrome arises post-conception from a zygote already aneuploid consequent to meiotic nondisjunction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0009-9163
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Risk effect of maternal age in Pallister i(12p) syndrome.
pubmed:affiliation
Children's Hospital of Pittsburgh, Department of Pediatrics.
pubmed:publicationType
Journal Article