Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1988-12-12
|
pubmed:abstractText |
To establish if CA 19-9 could detect early pancreatic cancer, we measured its serum concentration in 866 patients admitted for benign diseases and observed for 2 years. All patients with an elevated CA 19-9 level (greater than 40 units (U)/ml) were submitted to a computed tomography (CT) scan of the pancreas. The CA 19-9 level was increased in 117 patients. One hundred fifteen of these 117 patients had false-positive elevations. The CA 19-9 concentration was elevated mostly in benign hepatobiliary diseases. In this group of patients, CA 19-9 was correlated to alkaline phosphatase values. Eleven patients showed an elevated CA 19-9 level for 10 months without any malignancy developing. One patient had a normal CA 19-9 concentration 8 months before clinical signs of pancreatic carcinoma developed. We conclude that CA 19-9 measurement is of no value for the early detection of this malignancy.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0008-543X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2287-90
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:3179943-Aged,
pubmed-meshheading:3179943-Alkaline Phosphatase,
pubmed-meshheading:3179943-Antigens, Neoplasm,
pubmed-meshheading:3179943-False Positive Reactions,
pubmed-meshheading:3179943-Female,
pubmed-meshheading:3179943-Humans,
pubmed-meshheading:3179943-Liver Diseases,
pubmed-meshheading:3179943-Male,
pubmed-meshheading:3179943-Middle Aged,
pubmed-meshheading:3179943-Pancreatic Neoplasms,
pubmed-meshheading:3179943-Prospective Studies
|
pubmed:year |
1988
|
pubmed:articleTitle |
The evaluation of CA 19-9 antigen level in the early detection of pancreatic cancer. A prospective study of 866 patients.
|
pubmed:affiliation |
Clinique Médicale A, C.H.U. de Rouen, Hôpital de Bois-Guillaume, France.
|
pubmed:publicationType |
Journal Article
|