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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1988-11-21
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pubmed:abstractText |
Nineteen workers conducting mixing and high-volume airblast applications of the organophosphorus pesticide malathion were monitored simultaneously by biological monitoring and fluorescent tracer evaluation of dermal exposure. Complete 72-hr urine samples were collected and analyzed for dimethylthiophosphate and dimethyldithiophosphate metabolites. Dermal exposure was measured through the addition of a fluorescent tracer to the tank mix, subsequent examination of the skin surface under long-wave ultraviolet light, and fluorescence quantification with a video imaging system. Dermal exposure to applicators was correlated highly with total metabolite excretion (r = 0.91). Mixer exposure was not correlated significantly (r = 0.73) because of wide scatter in the data and the small number of workers monitored. Applicator exposures were more than 3 times higher than mixer exposures, reflecting the high exposure potential inherent in airblast spraying. Exposure to regions protected by gloves or clothing was more than 75% of total exposure for both mixers and applicators. These results provide evidence that the fluorescent tracer technique is a valid methodology for measuring relative levels of dermal exposure during agricultural work activities. The technique also holds promise as a quantitative procedure for evaluating the effectiveness of engineering control strategies and protective clothing performance.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/Malathion,
http://linkedlifedata.com/resource/pubmed/chemical/O,O-dimethyl phosphorodithioate,
http://linkedlifedata.com/resource/pubmed/chemical/O,O-dimethyl phosphorothionate,
http://linkedlifedata.com/resource/pubmed/chemical/Thiophosphoric Acid Esters
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-8894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
438-44
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3177222-Agriculture,
pubmed-meshheading:3177222-Environmental Exposure,
pubmed-meshheading:3177222-Environmental Monitoring,
pubmed-meshheading:3177222-Fluorescent Dyes,
pubmed-meshheading:3177222-Humans,
pubmed-meshheading:3177222-Malathion,
pubmed-meshheading:3177222-Protective Clothing,
pubmed-meshheading:3177222-Regression Analysis,
pubmed-meshheading:3177222-Skin,
pubmed-meshheading:3177222-Skin Absorption,
pubmed-meshheading:3177222-Thiophosphoric Acid Esters
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pubmed:year |
1988
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pubmed:articleTitle |
Correlation of fluorescent tracer measurements of dermal exposure and urinary metabolite excretion during occupational exposure to malathion.
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pubmed:affiliation |
Department of Environmental Science, New Jersey Agricultural Experiment Station, Cook College, Rutgers University, New Brunswick 08903.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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