Linked Life Data

3175837

Source:http://linkedlifedata.com/resource/pubmed/id/3175837

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-11-7
pubmed:abstractText
Prognostic criteria were developed to select children with high-risk brainstem gliomas for experimental treatment with hyperfractionated radiation. Patients were required to have (a) tumors confined primarily to the brainstem; (b) positive findings in two of three groups of neurologic signs (cranial nerve deficits and long-tract and cerebellar signs), and (c) symptom duration of less than 6 months. The 18-month survival of only 1 of 33 evaluable patients suggests that these criteria did in fact select tumors of poor prognosis. Such noninvasive predictors provide a valuable means of selecting for experimental treatment those children who would not be expected to benefit from standard therapies for malignant brainstem tumors. These criteria do not require routine biopsy for prognostic purposes, and avoid exposing the children to unnecessary risk.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0090-3019
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
276-80
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Prognostic criteria for experimental protocols in pediatric brainstem gliomas.
pubmed:affiliation
Department of Neurosurgery, University of Tennessee, Memphis.
pubmed:publicationType
Journal Article