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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1988-11-7
|
| pubmed:abstractText |
In a 3-year period 157 single lumen Broviac catheters were inserted in 145 children with various neoplastic diseases. The overall duration of the catheter courses was 30,533 days (median, 171; range, 2 to 647). Sixty-five percent of the catheter courses (102 of 157) were complicated by at least 1 febrile episode, for a total of 157 episodes. According to European Organization for Research on Treatment of Cancer criteria, 79 febrile episodes (50%) were classified as microbiologically documented infections, 57 (36%) with and 22 (14%) without septicemia; 31 (20%) as clinically documented infections; and 47 (30%) as possible infections. Of the 79 microbiologically documented infections 21 were catheter-related infections (CRI), 32 were catheter-unrelated infections and 26 were infections of unknown source. Only 48% of CRI occurred during neutropenia (less than 1000 neutrophils/mm3), compared with 88% of catheter-unrelated infections and 96% of infections of unknown origin (P = 0.00007). Gram-positive microorganisms (56% staphylococci) accounted for 78% of all isolates in CRI, 47% in catheter-unrelated infections and 43% in infections of unknown origins (P = 0.03). Fungi represented 12% of all isolates. Clinical and microbiologic resolution without removal of the catheter was achieved in 12 of 21 CRI (57%) and no patient died from a CRI. This study indicates that over 3 of 4 of CRI are caused by Gram-positive bacteria, occur in neutropenic and non-neutropenic patients (approximately 50%) and can be successfully treated without removing the catheter.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0891-3668
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
556-60
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3174299-Adolescent,
pubmed-meshheading:3174299-Agranulocytosis,
pubmed-meshheading:3174299-Bacteria,
pubmed-meshheading:3174299-Catheters, Indwelling,
pubmed-meshheading:3174299-Child,
pubmed-meshheading:3174299-Child, Preschool,
pubmed-meshheading:3174299-Cross Infection,
pubmed-meshheading:3174299-Female,
pubmed-meshheading:3174299-Humans,
pubmed-meshheading:3174299-Male,
pubmed-meshheading:3174299-Neoplasms,
pubmed-meshheading:3174299-Opportunistic Infections,
pubmed-meshheading:3174299-Sepsis
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Role of Broviac catheters in infections in children with cancer.
|
| pubmed:affiliation |
Department of Infectious Disease, University of Genoa, Italy.
|
| pubmed:publicationType |
Journal Article
|