Linked Life Data

3172476

Source:http://linkedlifedata.com/resource/pubmed/id/3172476

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-11-10
pubmed:abstractText
The clinical effects of diltiazem in 15 patients with congestive cardiomyopathy were observed. Symptoms were controlled in 66% and cardiac enlargement improved in 73.3%. There was a decrease in cardiac silhouette on X-ray in 18.82 +/- 3.2% (p less than 0.01), with an increase of EF(%), CO, CI and a decrease of TPR on two-dimensional (2-D) echocardiogram (p less than 0.01). Prior to treatment, the cardiac status of 8 cases was grade III and 7 cases grade IV; after treatment 1 case was grade I, 8 grade II, 5 grade III and 1 grade IV. This improvement might be due to the blockade of calcium channels and the fact that diltiazem has the least negative inotropic effect among the calcium antagonists. The dosage, route of administration, and prevention of side effects are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-4868
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-33
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A preliminary study on the therapeutic effects of a calcium antagonist (diltiazem) on primary congestive cardiomyopathy. A clinical survey of 15 cases.
pubmed:affiliation
Department of Cardiology, Chinese PLA General Hospital, Beijing.
pubmed:publicationType
Journal Article