Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1988-11-15
pubmed:abstractText
Recent evidence has suggested that the cariostatic effects of topical fluoride (F) are related to the presence of low concentrations of ionic F in the oral environment. The purpose of this study was to compare the retention of F in the oral environment over 24-hour periods after the use of a F dentifrice or a F rinse. Groups of ten consenting adult subjects (age 18-52 years) brushed and/or rinsed (B/R) in a standardized manner twice per day in the morning (AM) and before bed (PM) with either a placebo dentifrice (8 ppm F), NaF dentifrice (1100 ppm F), or NaF rinse (225 ppm F). Experiments were performed with placebo dentifrice only (PD); F dentifrice only (FD); F dentifrice followed by F rinse (FD/FR); placebo dentifrice followed by F rinse (PD/FR); and F rinse followed by placebo dentifrice (FR/PD). Unstimulated whole saliva samples were collected at baseline and then at 0, 15, 30, and 45 min, 1, 2, and 8 hr after B/R in the AM, after B/R in the PM and upon rising the following morning. Salivary flow rate and F were determined for each sampling interval. The results of this study suggest that: (1) F rinse may be a more effective way of delivering topical F than F dentifrice; (2) based on F retention, the combination of FD/FR was not more effective than FR only (PD/FR); (3) older individuals with gingival recession retained higher F levels; and (4) bedtime F application resulted in longer F retention than did daytime application, which may have important implications for enamel remineralization.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-0345
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1257-62
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Comparison of fluoride concentrations in unstimulated whole saliva following the use of a fluoride dentifrice and a fluoride rinse.
pubmed:affiliation
Eastman Dental Center, Rochester, New York 14620.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial