Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1988-11-2
pubmed:abstractText
A technique for assessing brain perfusion with magnetic resonance (MR) imaging is described. This technique uses two spin echo sequences that are identical except that the second is sensitised to blood flow by use of a pair of unipolar gradients on either side of the 180 degree pulse. Differences in phase between the two sequences are displayed with a sensitivity to flow rates of +/- 0.5, +/- 1, and +/- 2 mm/s per full scale (+/- pi radians) deflection. The technique was validated for measurement of flow at these rates with a water phantom. Ten patients with cerebrovascular disease, multiple sclerosis, cerebral tumor, periventricular leukomalacia, and meningitis were studied. Differences between grey and white matter were normally seen in adults. Infants displayed differences between central and peripheral regions of the brain. Abnormalities were seen in all clinical cases. The technique will require further validation but it appears to provide a totally noninvasive method for assessing brain perfusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0363-8715
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
721-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Assessment of brain perfusion with MR imaging.
pubmed:affiliation
GEC Hirst Research Laboratories, Wembley, Middlesex, England.
pubmed:publicationType
Journal Article