Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1988-11-23
|
| pubmed:abstractText |
Analysis of sex ratio in 301 siblings of 150 patients with early-onset pauciarticular juvenile rheumatoid arthritis revealed a male-to-female ratio of 1:2.00 in sibships with an HLA-B44+ proband, compared with a ratio of 1:1.05 in other sibships (G2 = 6.07, df = 1, p = 0.014). The siblings had a sex ratio of 1:0.8, when the HLA-B44 antigen was present in either parent but not transmitted to the proband. The capacity to distort the sex ratio was limited therefore to disease-associated HLA-B44 haplotypes.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0198-8859
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
227-33
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3170286-Adolescent,
pubmed-meshheading:3170286-Adult,
pubmed-meshheading:3170286-Arthritis, Juvenile Rheumatoid,
pubmed-meshheading:3170286-Child,
pubmed-meshheading:3170286-Child, Preschool,
pubmed-meshheading:3170286-Female,
pubmed-meshheading:3170286-HLA Antigens,
pubmed-meshheading:3170286-HLA-B Antigens,
pubmed-meshheading:3170286-HLA-B44 Antigen,
pubmed-meshheading:3170286-Haplotypes,
pubmed-meshheading:3170286-Humans,
pubmed-meshheading:3170286-Infant,
pubmed-meshheading:3170286-Male,
pubmed-meshheading:3170286-Sex Ratio
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
HLA and altered sex ratios in juvenile rheumatoid arthritis sibships.
|
| pubmed:affiliation |
Division of Rheumatology, Children's Hospital Medical Center, Cincinnati, OH 45229-2899.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|